ORGANIZATION OF DISINFECTION AFFAIR
pp. 5-20
DOI: 10.35411/2076-457X-2025-4-5-20
Development of typical production control programs an important element when rendering services to disinfection, desinsection and deratization
Yu.A. Zakharova1, Yu.V. Demina1,4, A.N. Anikin5, M.A. Galkina2, S.G. Starostina2, P.Yu. Bychkov3
1Disinfectology Institute of the Federal Scientific Center of Hygiene named after F.F. Erisman of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing: 141014, Mytishchi, Moscow region, 2 Semashko str., Russian Federation;
2Moscow Regional Disinfection Center: 143002, Moscow Region, Odintsovo, 12 Mozhayskoye Shosse, Russian Federation:
3Moscow City Disinfection Center: 129337, Moscow, 9 Yaroslavskoye Shosse, Russian Federation;
4Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russion Federation: 125993, Moscow, Barrikadnay str., 2/1, Russion Federation;
5Perm Regional Center for Disinfection: 614990, Perm, 5 Marshrutnaya Street, Russion Federation.
Production control is an integral part of managing production risks, complying with sanitary standards, and reducing the harmful effects of production factors on humans and the environment. Russian legislation requires all legal entities and private entrepreneurs to comply with the requirements for organizing and conducting production control. To this end, the developed production control programs allow for the identification of the most significant areas of activity. The article provides recommendations for developing standard production control programs for disinfection, dezinsection, deratization, chamber disinfection, and dezinsection services, including control blocks: documentation; disinfection, dezinsection, and deratization measures; chamber disinfection and dezinsection measures; disinfection agents; transport; equipment and personal protective equipment; production facilities; personnel; and biological waste. Each block defines the objects of control, measures, types of control, and their frequency. Analysis of production control data will help identify risk-generating violations and improve risk management measures, which will improve the quality of working conditions, ensure a comfortable living environment, and improve public health.
Keywords: production control, typical programs, disinfection, disinsection, deratization, and chamber treatment.
Authors
Zakharova Yulia Alexandrovna – Doctor of Medical Science, Professor, Scientific Supervisor, Institute of Disinfectology FBIS F.F. Erisman of Rospotrebnadzor; Tel.: +7 (495) 582-92-40, e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0003-3416-0902
Demina Yulia Viktorovna – Doctor of Medical Science, Associate Professor, Director, Institute of Disinfectology, FBIS F.F. Erisman of Rospotrebnadzor. ORCID ID: 0000-0003-0538-1992
Anikin Alexey Nikolaevich – Director of the Perm Regional Center for Disinfection
Galkina Margarita Alekseevna – Director of FSUE "Moscow Regional Disinfection Center"
Starostina Svetlana Gennadevna – Dezinfektologist of FSUE "Moscow Regional Disinfection Center"
Bychkov Pavel Yuryevich – Deputy Head for Medical Activities of the Joint-Stock Company "Moscow City Disinfection Center"
DISINFECTION
pp. 21-29
DOI: 10.35411/2076-457X-2025-4-21-29
Validation of a Gas Chromatography method for the determination of phenol and benzene derivatives in the joint presence in disinfectants
A.P. Terskova1, E.A. Kostenko1, A.A. Pavlovskaya2, L.I. Fedorina2, A.S. Zvereva1
1Disinfectology Institute of F.F. Erisman FSCH of Rospotrebnadzor: 117246, Moscow, Nauchniy proezd, 18a, Russian Federation;
2M.V. Lomosov Institute of Fine Chemical Technology of RTU-MIREA: 119571, Moscow, Vernadskogo ave., 86, Russian Federation.
Efficiency of disinfectants directly depends on the concentration of an active substance. Above 90 % of disinfectants performed as a combined composition containing two or more active substances. In this paper methodology for a selective determining of 6 phenol and benzene derivatives (p-dichlorobenzene, 2-phenoxyethanol, 1-phenoxy-2-propanol, 1,1’biphenyl-2-ol, 5-сhloro-2-(4-chlorophenoxy)phenol, and 5-сhloro-2-(2,4-dichlorophenoxy)phenol) using Gas Chromatography with flame ionization detector, as well as their quantitative estimation in the presence of a phenol as an inner standard are observed. The validation of a newly developed methodology was done. Limits of quantitation of the methodology proposed for the p-dichlorobenzene amounted to 0.0191 mg/ml, for the 2-phenoxyethanol – 0.0171 mg/ml, for the 1-phenoxy-2-propanol – 0.0279 mg/ml, for the 1,1’biphenyl-2-ol – 0.0343 mg/ml, for the 5-сhloro-2-(4-chlorophenoxy)phenol – 0.0139 mg/ml, for the 5-сhloro-2-(2,4-dichlorophenoxy)phenol – 0.0333 mg/ml. The approbation of the methodology using model disinfectants confirmed its high selectivity and possible application while determining phenol and benzene derivatives either separate, or in the joint presence in disinfectants as well as in prosses solutions.
Keywords: disinfectants, p-dichlorobenzene, 2-phenoxyethanol, 1-phenoxy-2-propanol, 1,1’biphenyl-2-ol, triclosan, tinosan, Gas Chromatography
Authors
Alisa Petrovna Terskova – Engineer, Disinfectology Institute of F.F. Erisman FSCH of Rospotrebnadzor; e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.
Evita Aleksandrovna Kostenko – Specialist, Disinfectology Institute of F.F. Erisman FSCH of Rospotrebnadzor
Arina Andreevna Pavlovskaya – Assistant Professor of the Department of Analytical Chemistry named after I.P. Alimarin of M.V. Lomosov Institute of Fine Chemical Technology of RTU-MIREA
Ludmila Ilyinichna Fedorina – Senior Professor of the Department of Analytical Chemistry named after I.P. Alimarin of M.V. Lomosov Institute of Fine Chemical Technology of RTU-MIREA
Anastasia Sergeevna Zvereva – Junior Researcher, Disinfectology Institute of F.F. Erisman FSCH of Rospotrebnadzor
pp. 30-41
DOI: 10.35411/2076-457X-2025-4-30-41
Analysis of the effectiveness of disinfectants against strains of fungi of the genus Aspergillus isolated from ventilation systems of medical organizations
E.V. Khaldeeva
FBUN Kazan Research Institute of Epidemiology and Microbiology of Rospotrebnadzor:420015, Russian Federation, Kazan, Bol’shaya Krasnaya st., 67.
Saprophytic fungi of the genus Aspergillus are widely distributed in nature and can act as etiological agents of nosocomial infections. The air environment, including ventilation systems, is one of the most common sources of their spread in medical facilities. To evaluate the effectiveness of different disinfection methods and disinfectants in relation 24 strains of Aspergillus spp. isolated from ventilation systems in medical facilities, three disinfection methods using five different disinfectants were tested . Disinfection methods recommended for ventilation and air conditioning systems (air ducts), as well as a method recommended for mold lesions were tested. The effectiveness of each method was evaluated using both the suspension and test object methods. The effectiveness of the recommended mode for mold lesions was confirmed when evaluated using the suspension method. However, the insufficient effectiveness of the mode recommended for disinfecting ventilation and air conditioning systems (air ducts) at the minimum permitted concentration of disinfectants was noted. The resistance of individual strains to one or several disinfectants was confirmed when using the modes recommended for the disinfection of ventilation and air conditioning systems (ducts).
Keywords: Aspergillus, disinfectants, disinfection mode, efficiency, air environment, ventilation, medical organizations, sensitivity, fungi.
Author
Khaldeeva Elena Vladimirovna – Candidate of Chemical Sciences, Leading Researcher, Head of the Mycology Laboratory of Kazan Research Institute of Epidemiology and Microbiology; Tel.: (843) 236-56-59, e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0002-4627-2162
DISINSECTION
pp. 41-49
DOI: 10.35411/2076-457X-2025-4-41-49
Antifeedant effect of cyantraniliprole and flonicamide on the german cockroach
O.Yu. Eremina, V.V. Olifer
Disinfectology Institute of the Federal Scientific Center of Hygiene named after F.F. Erisman of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing:117246, Russian Federation, Moscow, Nauchniy proezd, 18a.
The insecticidal activity of active substances promising for medical disinsection – cyantraniliprole (IRAC group 28) and flonicamid (IRAC group 29) – was studied, and their effect in sublethal concentrations on the feeding behavior of the German cockroach was assessed. The studies were conducted using the group feeding method. In the absence of mortality and weak reversible damage to female German cockroaches by S-NIID (insecticide-susceptibles) and KR (multiresistant) strains consuming poisoned bait at a sublethal concentration of 0.01 % cyantraniliprole, a significant decrease in the amount for bait consumed was shown, possibly due to inhibition of the feeding process. Over the 4 days of the experiment, the consumption of poisoned food by females, compared to alternative food, was 19.4 times lower for the S-NIID strain and 11.6 times lower for the KR strain. After initiating the feeding with insecticide bait and receiving the initial dose of the active substance, S-NIID strain females practically stopped eating on the 2nd-4th day of the experiment, and in females of the multiresistant KR strain, feeding activity decreased significantly on the 2nd day, but began to increase by the 3rd-4th day of the experiment. The bait in a sublethal concentration of 0.1 % flonicamid was also eaten by females worse than the alternative food: for the S-NIID strain by 3.9 times, for the KR strain by 5.6 times. Flonicamid in a sublethal concentration caused a decrease in the feeding intensity without its complete inhibition. The amount of feces, as an indirect indicator of food consumption, also confirmed the presence of antifeedant action of both insecticides. A promising direction should be considered the creation of insecticidal baits based on cyantraniliprole to combat the German cockroach, while the concentration of the active substance should be such that a single portion of the bait consumed by the insect contains a lethal dose. It is inappropriate to introduce flonicamid into the composition of food baits for the German cockroach. Keywords: Blattella germanica, antifeedants, cyantraniliprole, flonicamid, feces, feeding behavior.
Authors
Eremina Olga Yurevna – Doctor of Science in Biology; Leading Researcher of the Division of disinsection (with laboratory of entomology) of the Disinfectology Institute of the Center of Hygiene named after F.F. Erisman of Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing; e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0002-8268-2230
Olifer VeronikaValentinovna – PhD in Biological Sciences; Leading Researcher of the Division of disinsection (with laboratory of entomology) of the Disinfectology Institute of the Center of Hygiene named after F.F. Erisman of Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing. e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0002-4736-7905
pp. 50-58
DOI: 10.35411/2076-457X-2025-4-50-58
Trends in insecticide development: review, analysis, and prospects
O.Yu. Eremina, V.V. Olifer
Disinfectology Institute of the Federal Scientific Center of Hygiene named after F.F. Erisman of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing:117246, Russian Federation, Moscow, Nauchniy proezd, 18a.
Current trends in the development of new insecticides include reducing the environmental burden of pesticides, significantly reducing pesticide residues in agricultural products and the environment, and developing compounds that selectively target specific arthropod pests while being non-toxic to humans and non-target organisms. Despite the consolidation of companies researching pesticides, the average time to develop a new compound is approximately four years. During the first 50 years of organic insecticide development, at least 368 compounds were discovered, classified into 15 groups based on their mechanisms of action. Since the 1990s, 37 new groups have been discovered, comprising 93 compounds. The number of insecticide groups with unique mechanisms of action is increasing, but each group typically consists of one, or in rare cases, two, three, or more compounds. More and more groups of insecticides are emerging that selectively target specific pest species. Of the 37 new groups of active ingredients used in medical pest control in Russia, only 5 are neonicotinoids (10.9 % of pest control products), fiproles (8.3 %), oxadiazines (0.08 %), pyrroles (0.03 %), and spinosyns (0.01 %). The bulk of the market is accounted for by pyrethroids (58.7 %) and organophosphates (16.2 %). Of primary interest for medical pest control in our country are diamides (cyantraniliprole, chlorantraniliprole), isoxazolines (fluralaner, isocycloseram), meta-diamides (broflanilide), and several other groups. The growing resistance of arthropods to current insecticides is a serious global problem. To minimize risks to human health and the environment, the concept of an "Integrated Pest Management System" is being widely implemented. By 2050–2060, biopesticides are projected to outweigh synthetic insecticides in terms of usage. Keywords: resistance, insecticides, pesticides, environment, mechanisms of action.
Authors
Eremina Olga Yurevna – Doctor of Science in Biology; Leading Researcher of the Division of disinsection (with laboratory of entomology) of the Disinfectology Institute of the Center of Hygiene named after F.F. Erisman of Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing; e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0002-8268-2230
Olifer VeronikaValentinovna – PhD in Biological Sciences; Leading Researcher of the Division of disinsection (with laboratory of entomology) of the Disinfectology Institute of the Center of Hygiene named after F.F. Erisman of Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing. e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0002-4736-7905
EPIDEMIOLOGY
pp. 59-68
DOI: 10.35411/2076-457X-2025-4-59-68
Tick-borne viral encephalitis on the territory of the natural focus: features of the epidemic process in the context of preventive measures
E.V. Fedorova1, A.V. Somova1,2, T.E. Byba3
1Federal State Budgetary Educational Institution of Higher Education "Ural State Medical University" of the Ministry of Health of the Russian Federation: 620028, Yekaterinburg; Repina St. 3, Russian Federation;
2FBUZ "Center of Hygiene and Epidemiology in the Sverdlovsk Region": 620078, Yekaterinburg, per. Separate, 3, Russian Federation;
3Branch of the FBUZ "Center of Hygiene and Epidemiology in the Sverdlovsk Region in the Chkalovsky District of Yekaterinburg, the city of Polevskoy and Sysertsky District": 620130, Yekaterinburg, st. March 8, 177a, Russian Federation.
The Sverdlovsk region is an active natural focus of tick-borne viral encephalitis (TVE). Therefore, in the context of the continuing risks of the disease of the population, constant monitoring of the incidence of TVE, an analysis of complaints about tick suction, and an assessment of the effectiveness of anti-epidemic measures are required. The purpose of the study is to analyze the features of the epidemic process of TVE on the territory of the natural focus when implementing preventive measures (on the example of the district of Yekaterinburg). The data of the information system of epidemiological surveillance for TVE from 2012 to 2022 in the Sverdlovsk region, Yekaterinburg, Chkalovsky district of Yekaterinburg were studied. A retrospective epidemiological analysis of the incidence of TVE and cases of tick suction was carried out. It was revealed that the incidence of TVE among the population of the Chkalovsky district of Yekaterinburg ranged from 1.4 0/0000 to 4.9 0/0000, and the level of ticks affected by suction ranged from 251.7 0/0000 to 991.4 0/0000. At the same time, cases of TVE were recorded in all age groups, and the risk group was people over 40 years old. At the same time, the level of tick victims among the population of the Chkalovsky district did not exceed the indicators for Yekaterinburg and the Sverdlovsk region. However, in 2020–2021. in the area there was a significant decrease in the availability of medical care for tick suction compared to the city and the region. It has been established that the incidence of TVE depends on the population's reversibility about tick sucking and the level of icing. The role of vaccination of the population in the fight against TVE was noted. The vector of anti-epidemic (preventive) measures should be aimed at timely diagnosis of the disease, deratization and acaricidal treatments, an increase in adult vaccination coverage in accordance with the Regional Calendar of Preventive Vaccinations of the Sverdlovsk Region.
Keywords: tick-borne viral encephalitis, epidemic process, retrospective epidemiological analysis, morbidity, natural focus, anti-epidemic measures. 9
Authors
Fedorova Ekaterina Vladimirovna – Candidate of Sciences (Medicine), Associate Professor of the Department of Epidemiology, Social Hygiene and Organization of State Sanitary and Epidemiological Service; Tel.: (343) 214–86–90, e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0009-0005-4775-2159
Somova Anna Viktorovna – Candidate of Sciences (Medicine), Associate Professor of the Department of Epidemiology, Social Hygiene and Organization of State Sanitary and Epidemiological Service, Epidemiologist of the Center of Hygiene and Epidemiology in the Sverdlovsk Region, Federal Budgetary Institution of Public Health. ORCID ID: 0009-0007-3014-3407
Byba Tatiana Evgenievna – Epidemiologist of the Center of Hygiene and Epidemiology in the Sverdlovsk Region in the Chkalovsky District of Yekaterinburg, the City of Polevskoy, and the Sysert District, Federal Budgetary Institution of Public Health
MATERIALS OF CONFERENCE
Materials of scientific and practical conference and General meeting (34th congress) of members of NOD (November 12–13, 2025, Moscow)
p. 66
Report
p. 72
The catalogue of participant of exhibition
Life of National Organization of Disinfectionists (NOD)
p. 58
Congratulation new members of NOD