DISINFECTION
pp. 5-13
DOI: 10.35411/2076-457X-2024-3-5-13
Promising trends in creating and using phage therapy medicinal products
Yu.A. Zakharova1, V.G. Akimkin2, B.I. Aslanov3, O.S. Fedotova4
1F.F. Erisman Federal Scientific Centre of Hygiene: 141014, Russian Federation, Moscow region, Mytishchi, Semashko str., 2;
2Central Research Institute of Epidemiology: 111123, Russian Federation, Moscow, Novogireevskaya str., 3a;
3North-Western State Medical University named after I.I. Mechnikov: 191015, Russian Federation, St. Petersburg, Kirochnaya str., 41;
4Federal Scientific Research Institute of Viral Infections "Virome": 620030, Russian Federation, Yekaterinburg, Letnaya str., 23.
The article discusses the use of bacteriophages as a promising research area of creating effective and environmentally friendly tools and methods for combating antimicrobial resistance and natural pollution. Breakthrough technologies for developing customized polyvalent (complex) and genetically engineered phages as well as their structural elements will improve the quality of patient care, increase the epidemiological well-being of the population, reduce the risks of infectious and non-infectious morbidity and the toxic load on the environment. The above should be integrated into the up-to-date concept of the biological security of the state.
Keywords: bacteriophages, infections, environment, biological safety, antibiotic resistance.
Authors
Zakharova Yu.A. – Doctor of Medical Sciences, Professor, Scientific Supervisor, Institute of Disinfectology, FBIS F.F. Erisman Federal Scientific Centre of Hygiene Federal Service for Surveillance on Costumer Rights Protection and Human Wellbeing; Tel.: (495) 582-92-40. e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0003-3416-0902
Akimkin V.G. – Full Member of the Russian Academy of Sciences, Doctor of Medical Sciences, Professor, Director of the "Central Research Institute of Epidemiology" Federal Service for Surveillance on Costumer Rights Protection and Human Wellbeing. ORCID ID: 0000-0001-8139-0247
Aslanov B.I. – Doctor of Medical Sciences, Head of the Department of Epidemiology, Parasitology and Disinfectology of the I.I. Mechnikov North-Western State Medical University. ORCID ID: 0000-0002-6890-8096
Fedotova O.S. – Candidate щf Biological Sciences, Leading Researcher of the Federal Scientific Research Institute of Viral Infections "Virome" of the Federal Service for Surveillance on Costumer Rights Protection and Human Wellbeing. ORCID ID: 0000-0003-1928-8211
pp. 13-20
DOI: 10.35411/2076-457X-2024-3-13-20
The effectiveness of the use of disinfectants and specialized agents for the degradation of nucleic acid amplification products on laboratory surfaces
T.L. Zamotaeva, S.S. Trofimova, O.A. Abrosimova, E.A. Cherkashin, V.G. Akimkin
Federal Budgetary Institution of Science Central Research Institute of Epidemiology of Rospotrebnadzor: 111123, Russian Federation, Moscow, Novogireevskaya str., 3a.
The rapid development of the PCR method opens up new opportunities for science and diagnostics. At the same time, the steady increase in the number of studies conducted increases the risk of contamination and, as a consequence, false-positive results. Today there are many ways to solve this problem, but none of them is universal. This paper presents the results of a comparison of the use of disinfectants and special decontamination agents to eliminate contamination of laboratory surfaces with nucleic acid amplification products – PCR amplicons. Study of decontamination activity against short DNA fragments of 117 bp were carried out under conditions that most closely simulate contamination of laboratory surfaces with PCR products. The effectiveness of decontamination was assessed by the residual number of amplicons in swabs from working surfaces. The high efficiency of destruction of amplicons when treating plastic, glass and metal surfaces with special decontamination agents based on metal ions and disinfectants based on oxygen-containing compounds has been shown. At the same time, it has been shown that agents containing a peroxide radical are capable of destroying amplicons mainly in combination with UV irradiation. Based on the results obtained, the feasibility of using metal ion-based decontamination agents for rapid and effective surface treatment in laboratories using nucleic acid amplification methods was demonstrated.
Keywords: disinfectants, PCR, amplicons, decontamination.
Authors
Tatyana L. Zamotaeva – Researcher at the Center for Product Development and Innovation of the Central Research Institute of Epidemiology of Rospotrebnadzor. ORCID 0009-ID: 0003-9799-3749. Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript., tel.: + 7(495) 974-96-46, ext.3831
Svetlana S. Trofimova – Technologist-Developer of the Center for Product Development and Innovation of the Central Research Institute of Epidemiology of Rospotrebnadzor. ORCID ID: 0009-0009-3717-2870
Olga A. Abrosimova – Epidemiologist, Head of the Epidemiological Service of the Federal Budgetary Institution of Science Central Research Institute of Epidemiology of Rospotrebnadzor. ORCID ID: 0000-0002-4545-1804
Evgeniy A. Cherkashin – Ph.D., Head of the Center for Product Development and Innovation of the Central Research Institute of Epidemiology of Rospotrebnadzor. ORCID ID: 0000-0002-3627-6047
Vasily G. Akimkin – Doctor of Medical Sciences, Professor, Academician of the Russian Academy of Sciences, Director of the of the Central Research Institute of Epidemiology of Rospotrebnadzor$ ORCID ID: 0000-0003-4228-9044
pp. 20-24
DOI: 10.35411/2076-457X-2024-3-20-24
Aspects of safe use of modern disinfectants in dairy enterprises
B.V. Manevich, E.A. Burykina
All-Russian Dairy Research Institute: 115093, Russian Federation, Moscow,, ул. Lyusinovskaya st, 35, Building 7.
The article analyzes the main aspects of safe application of chemical disinfectants widely used at dairy enterprises. Effective disinfection at dairy enterprises is directly related to the production of high-quality, safe and competitive food products. When selecting a disinfectant for use at a dairy enterprise, a comprehensive evaluation is necessary not only for effectiveness, but also a multilateral consideration of its safe use. Increasing requirements to ecologization of milk processing enterprises dictate the search for new combinations of functional components in the formulations of chemical sanitizers. The article shows the necessity of consideration of adhesion properties of disinfectants, their corrosive activity and indifference to various materials used at food processing enterprises. It is suggested to control working chloroactive disinfectant solutions, first of all, obtained by electrolysis method, not only by the content of active chlorine, but also by the value of redox potential. The relevance of research aimed at studying the inhibitory properties of active substances and residual quantities of disinfectants on starter microflora and the importance of a systematic approach to the integrated assessment of all elements of safe use of disinfectants at dairy enterprises is formulated.
Keywords: disinfectants, toxicity and hazard, effect on human body, environmental safety, redox potential, corrosivity, chemical contamination, inhibition.
Authors
Manevich Boris Vladilenovich – Candidate of Technical Sciences, Head of the Sanitary Processing Laboratory of All-Russian Dairy Research Institute; Tel.: (499) 236-82-26, e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0001-5979-3808
Burykina Elena Aleksandrovna – Junior Researcher, Laboratory of Sanitization of All-Russian Dairy Research Institute. ORCID ID: 0009-0004-8920-7477
pp. 24-33
DOI: 10.35411/2076-457X-2024-3-24-33
To the question of improving methods for assessing the effectiveness of high-level disinfection of endoscopes
N.I. Eremeeva1,2,3, F.A. Mukabenov1, A.A. Serov1, A.S. Gonchar1, V.A. Novikov1, A.V. Ilyakova1
1Disinfectology Institute of the Center of Hygiene named after F.F. Erisman of Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing: 117246, Russian Federation, Moscow, Nauchniy proezd, 18a;
2FGBOU DPO "Russian Medical Academy of Continuing Professional Education" of the Ministry of Health of Russia: 125993, Moscow, st. Barrikadnaya, 2/1, building 1;
3NMRC of Tuberculosis and Infectious Diseases of the Ministry of Health of the Russian Federation: 620039, Russian Federation, Yekaterinburg, 22 Partsyezda st., 50.
Introduction. The test-strain Mycobacterium terrae DSM 43227 is used to determine the required exposure time at the sporicidal concentration of disinfectant and temperature (up to plus 60 °C) for high-level disinfection (HLD) of endoscopes with disinfection and washing machines (DWM). Ame: to study the viability of the test-strain M. terrae DSM 43227 when testing the effectiveness of disinfectants for HLD of endoscopes with DWM. Materials and methods. Sterile endoscopes (OLIMPUS GIF P10 gastroscope (n=4)) were contaminated with DSM 43227 suspension (109 CFU) and donors’ blood as organic debris. Preliminary and final cleaned were carried out, then control of effectiveness was. Further – HLD with DWM with and without the addition of disinfectant. The washouts from endoscopes were taken according to MU 3.1.3798-22 for control of HLD and inoculated with 0.1 mL of Levenstein-Jensen medium. The effectiveness of HLD with the addition of disinfectant must be 100 %, according to Guideline R 4.2.3676-20. The study of the effect of high temperatures in the ranges from plus (30±1) °C to plus (70±1) °C on the test-strain was carried out using the algorithm (RU 139587 from 11.12.2023). Results. After HLD in DWM, the CFU growth of the test strain was not detected in the programs: with and without the disinfectant, which contradicted the expected results. Additional studies were conducted to clarify the reasons for the absence of CFU growth in washouts from endoscopes treated with DWM without addition of the disinfectant. Preliminary and final cleaning was excluded from the full cycle of processing of endoscope. Only HLD in DWM with and without addition of disinfectant were performed – no growth of CFU of DSM 43227 was detected again. Sensitivity of test strain to temperature plus (60±1) °C after 30 min of exposure was detected. Conclusion. The revealed sensitivity of M. terrae DSM 4322 to the effect of a temperature of 60 °C casts doubt on the legitimacy of the use of the test-microorganism in the method of testing HLD of endoscopes with DWM and is the basis for finding new approaches and improving methods for assessing the effectiveness of disinfectants for HLD of endoscopes with DWM.
Keywords: high-level disinfection, preliminary and final cleaning, flexible endoscopes, disinfectants, disinfection and washing machines, test-strain.
Authors
Natalya I. Eremeeva – Candidate of Biological Sciences, Head of the Department of Disinfection and Sterilization (with Microbiology Laboratory) of Institute of Disinfectology of the Federal Scientific Center of Hygiene named after F.F.Erisman; Assistant Professor of the Department of Epidemiology and Disinfectology of Federal State Budgetary Educational Institution of Further Professional Education "Russian Medical Academy of Continuous Professional Education" of the Ministry of Healthcare of the Russia; Leading Researcher of the NMRC of Tuberculosis and Infectious Diseases of Ministry of Health of the Russian Federation. Tel.: (922) 295-63-99, e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0003-3637-2570
Fedor А. Mukabenov – Researcher, Department of Disinfection and Sterilization, Institute of Disinfectology of the Federal Scientific Center of Hygiene named after F.F. Erisman. ORCID ID: 0000-0002-5631-0775
Alexey A. Serov – Researcher, Department of Disinfection and Sterilization, Institute of Disinfectology of the Federal Scientific Center of Hygiene named after F.F. Erisman. ORCID ID: 0000-0002-3094-9992
Anzhelica S. Gonchar – Junior Researcher, Department of Disinfection and Sterilization, Institute of Disinfectology of the Federal Scientific Center of Hygiene named after F.F. Erisman. ORCID ID: 0000-0002-5815-5916
Novikov A. Vyacheslav – Junior Researcher, Department of Disinfection and Sterilization (q\with Microbiology Laboratory) of the Institute of Disinfection, F.F. Erisman. ORCID ID: 0000-0001-8858-5872
Anastasia V. Ilyakova – Researcher, Department of Disinfection and Sterilization, Institute of Disinfectology of the Federal Scientific Center of Hygiene named after F.F. Erisman. ORCID ID: 0000-0002-1867-3495
DISINSECTION
pp. 33-40
DOI: 10.35411/2076-457X-2024-3-33-40
Results of 2012–2024 monitoring of German cockroaches insecticide resistance in Russia
O.Yu. Eremina, V.V. Olifer
Disinfectology Institute of the Center of Hygiene named after F.F. Erisman of Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing: 117246, Russian Federation, Moscow, Nauchniy proezd, 18a.
During a 12-year monitoring of the German cockroach in Russia, samples were obtained from 20 populations of cockroaches from Moscow (9) and the Moscow region (2), Kaluga region (1), Yekaterinburg (5), Magnitogorsk (1), Blagoveshchensk (2). Insects were introduced into culture and grown in insectarium. The topical method was used to determine resistance ratios to 13 insecticides from 7 chemical groups. The method of contact with a glass surface was used to slow down the effect of cypermethrin, fipronil, chlorpyrifos and propoxur on 12 cultures of cockroaches. The resistance ratios of 15 cockroach cultures when fed baits based on 10 a.i. are given. The patchy distribution of resistance to insecticides in Moscow was confirmed – cockroaches collected in a residential apartment were more susceptible to pyrethroid-based drugs than from student dormitories, public catering facilities, or medical organizations. The high and extremely high resistance of the German cockroach to compounds of the pyrethroid group indicates the need to replace this group in rotation schemes. It is necessary to expand the presence of new groups in the range of insecticides used. For effective disinsection it is necessary to establish the level of resistance of the German cockroach at each site where it is supposed to be carried out.
Keywords: German cockroach, resistance, contact and intestinal action, insecticidal baits.
Authors
Eremina Olga Yurevna – Doctor of Science in Biology; Leading Researcher of the Division of disinsection (with laboratory of entomology) of the Institute of Disinfectology of the Federal Scientific Center of Hygiene named after F.F. Erisman of the Rospotrebnadzor; e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0002-8268-2230
Olifer Veronika Valentinovna – PhD in Biological Sciences; Leading Researcher of the Division of disinsection (with laboratory of entomology) of the Institute of Disinfectology of the Federal Scientific Center of Hygiene named after F.F. Erisman of the Rospotrebnadzor. ORCID ID: 0000-0002-4736-7905
pp. 41-48
DOI: 10.35411/2076-457X-2024-3-41-48
Entomopatogenic fungi for control of the german cockroach
K.S. Krivonos, O.Yu. Eremina, V.V. Olifer
Disinfectology Institute of the Center of Hygiene named after F.F. Erisman of Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing: 117246, Russian Federation, Moscow, Nauchniy proezd, 18a.
The use of mycoinsecticides can be an alternative to reduce chemical pollution in human dwellings. The use of Beauveria bassiana and Metarhizium anisopliae is gradually increasing, reaching commercial scale in such countries as Brazil, China, and Mexico. At the same time, significant progress has been made in understanding the molecular aspects of pathogenesis, allowing the selection of highly effective fungal strains. Differences in the susceptibility of adults and nymphs of the German cockroach Blattella germanica L. to entomopathogenic fungi was shown. The possibility of enhancing the pathogenicity of various types of fungi when integrated with insecticides in sublethal doses is considered. The German cockroach has evolved many physical barriers, behavioral traits, and physiological mechanisms that prevent infection by various entomopathogens. These barriers include the outer cuticle, inner cuticle, digestive tract and peritrophic membrane, and immunological barriers. Fungal conidia entering the cockroach’s digestive tract was inactivated by a combination of antimicrobial compounds produced by the cockroach and commensal microorganisms, intestinal pH and digestive enzymes. The microbiota of Bl. germanica may play a critical role in protecting cockroaches from fungal invasion and colonization.
Keywords: insecticide resistance, Blattella germanica, Beauveria bassiana, Metarhizium anisopliae, mycoinsecticides, entomopathogenic fungi.
Authors
Krivonos Kseniya Sergeevna – PhD in Biological Sciences; Senior Researcher of the Division of disinsection (with laboratory of entomology) of the Institute of Disinfectology of the Federal Scientific Center of Hygiene named after F.F. Erisman of the Rospotrebnadzor; Tel.: (495) 586-11-44 (ext. 1440), e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.; ORCID ID: 0000-0003-4633-6645
Eremina Olga Yurevna – Doctor of Science in Biology; Leading Researcher of the Division of disinsection (with laboratory of entomology) of the Institute of Disinfectology of the Federal Scientific Center of Hygiene named after F.F. Erisman of the Rospotrebnadzor. ORCID ID: 0000-0002-8268-2230
Olifer Veronika Valentinovna – PhD in Biological Sciences; Leading Researcher of the Division of disinsection (with laboratory of entomology) of the Institute of Disinfectology of the Federal Scientific Center of Hygiene named after F.F. Erisman of the Rospotrebnadzor. ORCID ID: 0000-0002-4736-7905
DERATIZATION
pp. 49-57
DOI: 10.35411/2076-457X-2024-3-49-57
The effect of the active substance content in a rodenticidal agent on the effectiveness of deratization treatments
V.Yu. Komarov1,2, E.I. Vikulina1
1Disinfectology Institute of the Center of Hygiene named after F.F. Erisman of Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing: 117246, Russian Federation, Moscow, Nauchniy proezd, 18a;
2FGBOU DPO "Russian Medical Academy of Continuing Professional Education" of the Ministry of Health of Russia: 125993, Moscow, st. Barrikadnaya, 2/1, building 1.
House mice, gray rats and other mouse-like rodents pose a threat to human health and cause significant damage to its activities. Despite significant advances in deratization practice, rodent control currently remains a significant problem, since these biological species have a unique genetic ability to rapidly recover and increase their numbers. The rodent control program should be based on data on the ecology, behavior and preferences of rodents, their sensitivity to active substances, the specific situation of a certain object and territory. Each species has its own characteristics. It is necessary to take into account species preferences when developing the composition and form of application of rodenticidal baits. It is important to ensure the achievement of target values in the consumption of the product by rodents, its effectiveness, safety in relation to non-target species and safety during its placement and use. It is necessary to take into account what concentration of the active substance (DV) for rodents will be fatal, how much rodenticidal bait will be required for their death and for how long this amount of bait will be eaten by them. The effectiveness of the conducted deratization treatments is directly influenced by the content of the active substance in the applied rodenticidal agent. The analysis of the effectiveness of rodenticidal baits with different contents of the active substance bromadiolone in relation to house mice and gray rats showed that with a decrease in the concentration of DV in the bait, the period from the beginning of its eating to the onset of irreversible changes in the body of rodents leading to their death occurs. The placement of baits during deratization treatments should take place taking into account the species characteristics of rodents. In terms of body weight, the amount of absorbed DV by the body of a house mouse in comparison with a gray rat when eating rodenticidal bait is significantly higher, which is observed in the average daily and total intake. But in quantitative terms, gray rats consume significantly more bait. For the death of a house mouse, an average of about 8 g of bait is required with a bromadiolone content of 0.005 %, and the minimum amount was 3.2 g. For a gray rat, the average amount of bait was 32.4 g, and the minimum ~ 10 g. Taking into account these data, the amount of bait placed at the facility will vary from the number of rodents and the feedability of baits. A lower content of DV in baits contributes to an increase in their consumption during deratization treatments. With a high number of rodents, the amount of bait placed must be multiplied.
Keywords: synanthropic rodents, gray rat, house mouse, deratization measures, anticoagulants, bromadiolone.
Authors
Vladimir Yu. Komarov – Candidate of Veterinary Sciences, Associate Professor, Head of the Department, leading researcher of the Department of Deratization (with the laboratory for the study of rodents) of Institute of Disinfectology Federal Budgetary Estabishment of Sciences "F.F. Erisman Federal Scientific Center of Hygiene" of the Federal Service for Surveillance on Consumer Rights Protection and Human Wel-being; tel. (910) 305-38-72, е-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0002-1715-3199
Ekaterina Ig. Vikulina – Engineer of Chemical Department (with analytical methods laboratory) of Institute of Disinfectology Federal Budgetary Estabishment of Sciences "F.F. Erisman Federal Scientific Center of Hygiene" of the Federal Service for Surveillance on Consumer Rights Protection and Human Wel-being. ORCID ID: 0000-0002-8304-2622
ORGANIZATION OF DISINFECTION Affairs
pp. 57-63
DOI: 10.35411/2076-457X-2024-3-57-63
Procedure and peculiarities of disinfectological examination
B.A. Zhigarlovsky1,2
1Disinfectology Institute of the Center of Hygiene named after F.F. Erisman of Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing: 117246, Russian Federation, Moscow, Nauchniy proezd, 18;
2FGBOU DPO "Russian Medical Academy of Continuing Professional Education" of the Ministry of Health of Russia: 125993, Moscow, st. Barrikadnaya, 2/1, building 1.
The article deals with the legislative basis and peculiarities of disinfectological examination and state registration of disinfectants (disinfectants, disinfection and deratization agents), and also considers the difficulties arising in the course of these procedures. Keywords: disinfection expertise, state registration of disinfectants, state registration of products, declaration of conformity, certificate of state registration
Author
Zhigarlovskii Bronislav Andreyevich – Ph.D. in Medicine, Head of the Department of disinfectological expertise of the Institute of disinfectology F.F. Erisman FSCH of Rospotrebnadzor; Associate Professor of the Department of Epidemiology and Disinfectology FSBEI FPE RMACPE MOH Russia; Tel.: (495) 586-11-44, e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0002-2982-0112
PRACTICE OF DISINFECTION Affairs
pp. 64-67
DOI: 10.35411/2076-457X-2024-3-64-67
The use of ultrasonic cavitation in the sanitation of dishes in the catering system
M.R. Yakhina, G.A. Allayarova, Е.Е. Zelenkovskaya, R.A. Daukaev, L.M. Masyagutova, G.R. Mironova
Ufa Research Institute of Occupational Health and Human Ecology: 450106. RussianFederation, Republic of Bashkortostan, Ufa, Stepana Kuvykina St., 94.
Kitchen and dining utensils can become a transmission link for infection, which can affect the development of the catering system. The degree of cleanliness of the dishes depends to a large extent on the diligence of the worker washing the dishes at the enterprise; Objective factors of tableware’s compliance with regulatory parameters also include uneven traffic flow of visitors throughout the day. Analysis of scientific literature contributed to the search for a solution to the problem of increasing the reliability of cleanliness of dishes while reducing, first of all, physical costs for auxiliary workers in school canteens and prompted the development of a patent "Method of washing tableware manually in public catering organizations," based on the use of cheap ultrasonic washing machines during the secondary washing and rinsing stages. As a positive effect, we noted the possibility of reducing the temperature of the water used by 20–25 °C, the refusal of an additional measure – the use of a disinfectant during quarantine or a pandemic; compliance of the final result with HACCP (Hazard Analysis and Critical Control Points) requirements and a reduction in the load on the worker washing the dishes. Thus, the implementation of the proposed method, according to the authors, is economically profitable and can have a health-preserving effect on both visitors to catering establishments and the worker washing the dishes.
Keywords: ultrasound, changes in the production process, HACCP, quality of work performed.
Authors
Yakhina Margarita R. – Cand. Sci. (Biol.), Associate Professor Senior Researcher of the Department of Occupational Medicine of URIOHHE; Tel.: (347) 255-46-21, e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0003-2692-372X
Allayarova Guzel A. – Cand. Sci. (Biol.), Senior Researcher of the Department of Analytical Chemistry of URIOHHE. ORCID ID: 0000-0003-0838-3598
Zelenkovskaya Еvgeniya Е. – Junior Researcher of the Department of Analytical Chemistry of URIOHHE. ORCID ID: 0000-0001-7682-2703
Daukaev Rustem A. – Cand. Sci. (Biol.), Head of the Laboratory of the Department of Analytical Chemistry of URIOHHE. ORCID ID: 0000-0002-0421-4802
Masyagutova Lyailya M. – Doc. Sci. (Med.), Chief Researcher, Head of the Department of Occupational Medicine of URIOHHE. ORCID ID: 0000-0003-0195-8862
Mironova Gulnara R. – Head of the consultative and outpatient department, occupational pathologist of the clinic of URIOHHE. ORCID ID: 0000-0002-9873-7611
EPIDEMIOLOGY
pp. 67-74
DOI: 10.35411/2076-457X-2024-3-67-74
Assessment of long-term dynamics of measles incidence
A.S. Pankov, V.V. Solovykh, O.V. Nuriakhmetova
Orenburg State Medical University (OrSMU): 460000, Russian Federation, Orenburg, Sovetckaya st. 6.
The paper examines the relevance of the measles problem in the Russian Federation, Volga Federal District, and Orenburg Region among various age groups. The manifestations of the measles epidemic process in long-term dynamics from 2010 to 2022 were studied and analyzed. A retrospective epidemiological analysis of the incidence of measles in the population was carried out, including an analysis of the long-term dynamics of the incidence of the population, an analysis of the intra-annual dynamics of the incidence and an analysis of the long-term dynamics of the incidence among various population groups. It has been established that the long-term average incidence of measles in the Orenburg region exceeds that in the Volga Federal District. Areas at risk for measles incidence among municipalities of the Orenburg region are Sorochinsky and Tashlinsky districts. The risk group for measles incidence in the Orenburg region is the child population. Two full cycles of rise and fall in morbidity have been established. In the intra-annual dynamics of the incidence of whooping cough, spring-winter seasonality is noted.
Keywords: measles, retrospective epidemiological analysis, risk areas, risk groups, time of risk, incidence.
Authors
Pankov Aleksandr Sergeevich – Associate Professor, Doctor of Medical Sciences, Head of Department of Epidemiology and Infectious Diseases of OrSMU; Tel.: (922) 818-80-44, e-mail: Адрес электронной почты защищен от спам-ботов. Для просмотра адреса в вашем браузере должен быть включен Javascript.. ORCID ID: 0000-0003-4994-6633
Solovykh Vitaliy Vasilevich – Candidate of Medical Sciences, Associate Professor of Department of Epidemiology and Infectious Diseases of OrSMU. ORCID ID: 0000-0001-5753-7405
Nuriakhmetova Olga Viktorovna – Candidate of Medical Sciences, Associate Professor of Department of Epidemiology and Infectious Diseases of OrSMU. ORCID ID: 0009-0008-2147-5343
Life of National Organization of Disinfectionists (NOD)
p. 48
Congratulation new members of NOD